Acetyl-Calpastatin (184-210) (human)

目录号: A15290

Selective calpain inhibitor

Acetyl-Calpastatin (184-210) (human)

Acetyl-Calpastatin (184-210) (human) Chemical Structure

CAS NO. 123714-50-1

Acetyl-Calpastatin (184-210) (human), selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 uM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.

库存: 现货

规格 价格 数量
1 mg
¥ 2,350.00
5 mg
¥ 6,350.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Acetyl-Calpastatin (184-210) (human), selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 uM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 3.15 mL 15.73 mL 31.47 mL
0.5 mM 0.63 mL 3.15 mL 6.29 mL
1 mM 0.31 mL 1.57 mL 3.15 mL
5 mM 0.06 mL 0.31 mL 0.63 mL

*The above data is based on the productmolecular weight 3177.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15290
MECHANISM OF ACTION Inhibitor
M. Wt 3177.65
Formula C142H230N36O44S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 123714-50-1
Synonyms N/A
SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O

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