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ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor with an IC50 of 3 nM and is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.71 mL | 143.53 mL | 287.07 mL |
| 0.5 mM | 5.74 mL | 28.71 mL | 57.41 mL |
| 1 mM | 2.87 mL | 14.35 mL | 28.71 mL |
| 5 mM | 0.57 mL | 2.87 mL | 5.74 mL |
*The above data is based on the productmolecular weight 348.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19985 |
|---|---|
| M. Wt | 348.35 |
| Formula | C17H18F2N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1708113-43-2 |
| Synonyms | ACY1083, ACY 1083 |
| SMILES | FC(CC1)(F)CCC1(NC2=NC=C(C(NO)=O)C=N2)C3=CC=CC=C3 |
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