ACY-1215 (Rocilinostat)

Name: ACY-1215 (Rocilinostat)
SKU: A11940
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A11940

HDAC6 抑制剂

ACY-1215 选择性地靶向并结合到 HDAC6，通过 Hsp90 的过度乙酰化干扰 Hsp90 蛋白质伴侣系统，并阻止随后的聚集体蛋白质降解。

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Grouped product items
规格	价格	库存
5mg	¥140.00	现货
10mg	¥245.00	现货
50mg	¥490.00	现货
100mg	¥770.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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Data Sheet

SDS

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生物活性

Discription

ACY-1215 selectively targets and binds to HDAC6, thereby disrupting the Hsp90 protein chaperone system through hyperacetylation of Hsp90 and preventing the subsequent aggresomal protein degradation.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11940
分子式	C24H27N5O3
分子量	433.5
CAS号	1316214-52-4
SMILES	C1=CC=C(C=C1)N(C2=CC=CC=C2)C3=NC=C(C=N3)C(=O)NCCCCCCC(=O)NO
其他名称	ACY1215
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	73 mg/mL (168.39 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.07 mL	115.34 mL	230.68 mL
0.5 mM	4.61 mL	23.07 mL	46.14 mL
1 mM	2.31 mL	11.53 mL	23.07 mL
5 mM	0.46 mL	2.31 mL	4.61 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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