ACY-738
ACY-738 是一种效力强大且选择性高的 HDAC6 抑制剂，具有改善的大脑生物利用度。ACY-738 以低纳摩尔的效力抑制 HDAC6，并且对于 I 类 HDACs 的选择性为 60 至 1500 倍。
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Adooq用户使用ACY-738发表的2篇文献
生物活性
| Discription | ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs. | |||||
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| Cell Research |
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产品信息
| 目录号 | A15934 |
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| 分子式 | C14H14N4O2 |
| 分子量 | 270.29 |
| CAS号 | 1375465-91-0 |
| SMILES | O=C(C1=CN=C(NC2(C3=CC=CC=C3)CC2)N=C1)NO |
| 其他名称 | ACY 738, ACY738 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 46 mg/mL (170.18 mM) | |
| Water | Insoluble | ||
| Ethanol | 1 mg/mL (3.69 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37 mL | 184.99 mL | 369.97 mL |
| 0.5 mM | 7.4 mL | 37 mL | 73.99 mL |
| 1 mM | 3.7 mL | 18.5 mL | 37 mL |
| 5 mM | 0.74 mL | 3.7 mL | 7.4 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1375465-91-0 | 1375465-91-0 供应商 | 1375465-91-0 花费 | 1375465-91-0 生产商 | 订购 1375465-91-0 | 1375465-91-0 代理商