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ACY-738

促销

HDAC6 抑制剂

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产品目录号: A15934

库存状态:中国现货中国现货

产品名 目录号 价格 数量
ACY-738 5mg A15934-5
¥ 1,000.00
ACY-738 10mg A15934-10
¥ 1,800.00
ACY-738 25mg A15934-25
¥ 4,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.

ACY-738

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 ACY-738 发表的文献 (1)
  • Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48

Chemical Information

目录号 A15934
Mechanism of action Inhibitor
分子量 270.29
化学分子式 C14H14N4O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1375465-91-0
Synonyms ACY 738, ACY738
SMILES code O=C(C1=CN=C(NC2(C3=CC=CC=C3)CC2)N=C1)NO
化学名称 N-Hydroxy-2-[(1-phenylcyclopropyl)amino]-5-pyrimidinecarboxamide

生物活性

Description
ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37 mL 184.99 mL 369.97mL
0.5 mM 7.4 mL 37 mL 73.99 mL
1 mM 3.7 mL 18.5 mL 37 mL
5 mM 0.74 mL 3.7 mL 7.4 mL

*The above data is based on the productmolecular weight 270.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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