ACY-775
目录号: A12456
HDAC6 抑制剂
ACY-775是一种强效且选择性的组蛋白去乙酰化酶6(HDAC6)抑制剂,其IC50为7.5纳摩尔。
| Discription | ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5?nM. | ||
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| 目录号 | A12456 |
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| 分子式 | C17H19FN4O2 |
| 分子量 | 330.36 |
| CAS号 | 1375466-18-4 |
| SMILES | O=C(NO)C(C=N1)=CN=C1NC2(CCCCC2)C3=CC=CC(F)=C3 |
| 其他名称 | ACY775, ACY 775 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 63 mg/mL (190.7 mM) | |
| Water | Insoluble | ||
| Ethanol | 63 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.27 mL | 151.35 mL | 302.7 mL |
| 0.5 mM | 6.05 mL | 30.27 mL | 60.54 mL |
| 1 mM | 3.03 mL | 15.14 mL | 30.27 mL |
| 5 mM | 0.61 mL | 3.03 mL | 6.05 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2