AD80
            目录号: A19332
    
RET/RAF/SRC/S6K 抑制剂
AD80 是一种多激酶抑制剂,能够抑制 RET、RAF、SRC 和 S6K,同时大幅降低 mTOR 活性。
 
        RET/RAF/SRC/S6K 抑制剂
| Discription | AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity. | ||
|---|---|---|---|
| Targets | 
 | 
| 目录号 | A19332 | 
|---|---|
| 分子式 | C22H19F4N7O | 
| 分子量 | 473.43 | 
| CAS号 | 1384071-99-1 | 
| SMILES | O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C3=NN(C(C)C)C4=NC=NC(N)=C43)C=C2 | 
| 其他名称 | AD 80, AD-80 | 
| 储存条件 | Store lyophilized at -20ºC, keep desiccated.  | 
| In vitro (25°C) | DMSO | 91 mg/mL (192.21 mM) | |
| Water | Insoluble | ||
| Ethanol | 91 mg/mL | ||
| In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 3 mg/mL | |
| *  <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg | 
|---|---|---|---|
| 0.1 mM | 21.12 mL | 105.61 mL | 211.22 mL | 
| 0.5 mM | 4.22 mL | 21.12 mL | 42.24 mL | 
| 1 mM | 2.11 mL | 10.56 mL | 21.12 mL | 
| 5 mM | 0.42 mL | 2.11 mL | 4.22 mL | 
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2