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AD80

产品详情

生物活性

AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity.

溶解度 *

In vitro (25°C)	DMSO	91 mg/mL (192.21 mM)
	Water	Insoluble
	Ethanol	91 mg/mL
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.12 mL	105.61 mL	211.22 mL
0.5 mM	4.22 mL	21.12 mL	42.24 mL
1 mM	2.11 mL	10.56 mL	21.12 mL
5 mM	0.42 mL	2.11 mL	4.22 mL

*The above data is based on the productmolecular weight 473.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19332
M. Wt	473.43
Formula	C22H19F4N7O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1384071-99-1
Synonyms	AD 80, AD-80
SMILES	O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C3=NN(C(C)C)C4=NC=NC(N)=C43)C=C2