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Adavivint

Adavivint

Name: Adavivint
SKU: A19257

目录号: A19257

Wnt signaling inhibitor

Adavivint Chemical Structure

CAS NO. 1467093-03-3

Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.

库存：现货

规格	价格	数量
5 mg	￥ 1,260.00
10 mg	￥ 2,170.00
50 mg	￥ 6,440.00
100 mg	￥ 12,880.00

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生物活性

Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.

溶解度 *

In vitro	DMSO	30 mg/mL (59.34 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.78 mL	98.9 mL	197.8 mL
0.5 mM	3.96 mL	19.78 mL	39.56 mL
1 mM	1.98 mL	9.89 mL	19.78 mL
5 mM	0.4 mL	1.98 mL	3.96 mL

*The above data is based on the productmolecular weight 505.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19257
M. Wt	505.55
Formula	C29H24FN7O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1467093-03-3
Synonyms	SM04690, SM 04690, SM-04690; Lorecivivint
SMILES	CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN=C1)=O