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ADL5859 HCl

促销

Opioid Receptor 激动剂

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产品目录号: A11072

库存状态:中国现货中国现货

产品名 目录号 价格 数量
ADL5859 HCl 5mg A11072-5
¥ 1,200.00
ADL5859 HCl 10mg A11072-10
¥ 2,000.00
ADL5859 HCl 50mg A11072-50
¥ 5,800.00
ADL5859 HCl 100mg A11072-100
¥ 8,800.00
ADL5859 HCl 10mM * 1mL in DMSO A11072-10mM-D
¥ 1,400.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

ADL5859 HCl is a highly potent and selective δ opioid receptor agonist with Ki value to be 0.84 nM and ED50 value to be 20 nM.

ADL5859 HCl

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Chemical Information

目录号 A11072
Mechanism of action Agonist
分子量 429
化学分子式 C24H28N2O3.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 850173-95-4
Synonyms ADL-5859
SMILES code CCN(CC)C(=O)C1=CC=C(C=C1)C2=CC3(CCNCC3)OC4=C2C(=CC=C4)O.Cl
化学名称 N,N-Diethyl-4-(5-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-4-yl)benzamide hydrochloride

生物活性

Description
ADL5859 HCl is a highly potent and selective δ opioid receptor agonist with Ki value to be 0.84 nM and ED50 value to be 20 nM.
Targets
δ-opioid receptor μ-opioid receptor κ-opioid receptor
0.8 nM(Ki)32 nM(Ki)37 nM(Ki)

溶解性

Solubility (25°C) * In vitro DMSO 86 mg/mL (200.48 mM)
Water 5 mg/mL (11.65 mM)
Ethanol 1 mg/mL (2.33 mM)
In vivo 0.5% hydroxyethyl cellulose/0.1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.31 mL 116.55 mL 233.1mL
0.5 mM 4.66 mL 23.31 mL 46.62 mL
1 mM 2.33 mL 11.66 mL 23.31 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 429. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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