ADX-47273

目录号: A11181

mGluR5 modulator

ADX-47273

ADX-47273 Chemical Structure

CAS NO. 851881-60-2

ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
10 mg
¥ 800.00
50 mg
¥ 2,900.00
100 mg
¥ 5,200.00
10mM * 1mL in DMSO
¥ 550.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.

Targets
mGlu5
0.17 μM(EC50)
In vitro (25°C) DMSO 74 mg/mL (200.34 mM)
Water <1 mg/mL (<1 mM)
Ethanol 30 mg/mL (81.22 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 12 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.07 mL 135.37 mL 270.74 mL
0.5 mM 5.41 mL 27.07 mL 54.15 mL
1 mM 2.71 mL 13.54 mL 27.07 mL
5 mM 0.54 mL 2.71 mL 5.41 mL

*The above data is based on the productmolecular weight 369.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11181
MECHANISM OF ACTION Modulator
M. Wt 369.36
Formula C20H17F2N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 851881-60-2
Synonyms ADX47273
SMILES C1C[C@@H](CN(C1)C(=O)C2=CC=C(C=C2)F)C3=NC(=NO3)C4=CC=C(C=C4)F

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