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mGluR5 modulator

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产品目录号: A11181


产品名 目录号 价格 数量
ADX-47273 5mg A11181-5
¥ 500.00
ADX-47273 10mg A11181-10
¥ 800.00
ADX-47273 50mg A11181-50
¥ 2,900.00
ADX-47273 100mg A11181-100
¥ 5,200.00
ADX-47273 10mM * 1mL in DMSO A11181-10mM-D
¥ 550.00



ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11181
Mechanism of action Modulator
分子量 369.36
化学分子式 C20H17F2N3O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 851881-60-2
Synonyms ADX47273
SMILES code C1C[C@@H](CN(C1)C(=O)C2=CC=C(C=C2)F)C3=NC(=NO3)C4=CC=C(C=C4)F
化学名称 (S)-(4-fluorophenyl)-(3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]piperidin-1-yl)methanone



ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5.

0.17 μM(EC50)


Solubility (25°C) * In vitro DMSO 74 mg/mL (200.34 mM)
Water <1 mg/mL (<1 mM)
Ethanol 30 mg/mL (81.22 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 12 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.07 mL 135.37 mL 270.74mL
0.5 mM 5.41 mL 27.07 mL 54.15 mL
1 mM 2.71 mL 13.54 mL 27.07 mL
5 mM 0.54 mL 2.71 mL 5.41 mL

*The above data is based on the productmolecular weight 369.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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