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P2X3/P2X2/3 receptor 拮抗剂

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产品目录号: A13131


产品名 目录号 价格 数量
AF-353 5mg A13131-5
¥ 900.00
AF-353 10mg A13131-10
¥ 1,600.00
AF-353 25mg A13131-25
¥ 3,500.00



AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0).





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Chemical Information

目录号 A13131
Mechanism of action Antagonist
分子量 400.21
化学分子式 C14H17IN4O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 865305-30-2
Synonyms AF353, AF 353
化学名称 5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine


AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0).


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.99 mL 124.93 mL 249.87mL
0.5 mM 5 mL 24.99 mL 49.97 mL
1 mM 2.5 mL 12.49 mL 24.99 mL
5 mM 0.5 mL 2.5 mL 5 mL

*The above data is based on the productmolecular weight 400.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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