AF-353
目录号: A13131
P2X3/P2X2/3 receptor 拮抗剂
AF-353 是一种新型、高效且可口服的 P2X3/P2X2/3 受体拮抗剂，能够抑制人类和大鼠的 P2X3（pIC50= 8.0）。
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生物活性
| Discription | AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0). | |||||
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产品信息
| 目录号 | A13131 |
|---|---|
| 分子式 | C14H17IN4O2 |
| 分子量 | 400.21 |
| CAS号 | 865305-30-2 |
| SMILES | CC(C)C1=CC(=C(C=C1OC2=CN=C(N=C2N)N)I)OC |
| 其他名称 | AF353, AF 353 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 86 mg/mL (214.88 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (7.49 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.99 mL | 124.93 mL | 249.87 mL |
| 0.5 mM | 5 mL | 24.99 mL | 49.97 mL |
| 1 mM | 2.5 mL | 12.49 mL | 24.99 mL |
| 5 mM | 0.5 mL | 2.5 mL | 5 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 865305-30-2 | 865305-30-2 供应商 | 865305-30-2 花费 | 865305-30-2 生产商 | 订购 865305-30-2 | 865305-30-2 代理商