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Afabicin

目录号: A19501
Afabicin(Debio 1450)是 Debio1452 的前体药物,专门针对葡萄球菌,对其他革兰氏阳性或革兰氏阴性菌种没有显著活性。Debio1452 是 FabI 抑制剂,FabI 是葡萄球菌中脂肪酸生物合成的关键酶。
Grouped product items
规格 价格 库存 数量
1mg
¥2,205.00
现货
5mg
¥3,255.00
现货
10mg
¥5,460.00
现货
25mg
¥8,575.00
现货
50mg
¥11,165.00
现货
100mg
¥16,975.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Afabicin (Debio 1450) is the prodrug of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
产品信息
目录号 A19501
分子式 C23H24N3O7P
分子量 485.43
CAS号 1518800-35-5
SMILES O=P(O)(O)OCN1C2=NC=C(/C=C/C(N(C)CC(OC3=CC=CC=C43)=C4C)=O)C=C2CCC1=O
其他名称 Debio 1450, Debio1450, Debio-1450; AFN-1720, AFN1720, AFN 1720
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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