Afabicin
目录号: A19501
Afabicin(Debio 1450)是 Debio1452 的前体药物,专门针对葡萄球菌,对其他革兰氏阳性或革兰氏阴性菌种没有显著活性。Debio1452 是 FabI 抑制剂,FabI 是葡萄球菌中脂肪酸生物合成的关键酶。
Discription | Afabicin (Debio 1450) is the prodrug of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. |
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目录号 | A19501 |
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分子式 | C23H24N3O7P |
分子量 | 485.43 |
CAS号 | 1518800-35-5 |
SMILES | O=P(O)(O)OCN1C2=NC=C(/C=C/C(N(C)CC(OC3=CC=CC=C43)=C4C)=O)C=C2CCC1=O |
其他名称 | Debio 1450, Debio1450, Debio-1450; AFN-1720, AFN1720, AFN 1720 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2