Afuresertib

目录号: A16392

Akt inhibitor

Afuresertib

Afuresertib Chemical Structure

CAS NO. 1047644-62-1

Afuresertib is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Afuresertib is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.4 mL 117.01 mL 234.02 mL
0.5 mM 4.68 mL 23.4 mL 46.8 mL
1 mM 2.34 mL 11.7 mL 23.4 mL
5 mM 0.47 mL 2.34 mL 4.68 mL

*The above data is based on the productmolecular weight 427.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16392
MECHANISM OF ACTION Inhibitor
M. Wt 427.32
Formula C18H17Cl2FN4OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1047644-62-1
Synonyms GSK 2110183, GSK2110183, GSK-2110183
SMILES CN1C(=C(C=N1)Cl)C2=C(SC(=C2)C(=O)NC(CC3=CC(=CC=C3)F)CN)Cl

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