Afuresertib

目录号: A16392

Akt 抑制剂

Afuresertib

Afuresertib Chemical Structure

CAS NO. 1047644-62-1

Afuresertib是一种有效的口服生物利用性Akt抑制剂,对于Akt1,Akt2和Akt3,Ki分别为0.08 nM,2 nM和2.6 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 750.00
10 mg
¥ 1,050.00
50 mg
¥ 2,950.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Afuresertib是一种有效的口服生物利用性Akt抑制剂,对于Akt1,Akt2和Akt3,Ki分别为0.08 nM,2 nM和2.6 nM。
In vitro DMSO 79 mg/mL (184.87 mM)
Water Insoluble
Ethanol 79 mg/mL (184.87 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.4 mL 117.01 mL 234.02 mL
0.5 mM 4.68 mL 23.4 mL 46.8 mL
1 mM 2.34 mL 11.7 mL 23.4 mL
5 mM 0.47 mL 2.34 mL 4.68 mL

*The above data is based on the productmolecular weight 427.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16392
作用机制 Inhibitor (抑制剂)
M. Wt 427.32
Formula C18H17Cl2FN4OS
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1047644-62-1
Synonyms GSK 2110183, GSK2110183, GSK-2110183
SMILES CN1C(=C(C=N1)Cl)C2=C(SC(=C2)C(=O)NC(CC3=CC(=CC=C3)F)CN)Cl

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