AG-1024 (Tyrphostin)

Name: AG-1024 (Tyrphostin)
SKU: A11400
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A11400

IGF-1R 抑制剂

1 篇发表文献

AG-1024（Tyrphostin）是一种特异性抑制剂，针对胰岛素样生长因子-1（IGF-1）和胰岛素受体酪氨酸激酶活性。对IGF-1的IC50值低于对胰岛素受体的IC50值。同时也能抑制胰岛素刺激的细胞增殖。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥560.00	现货
25mg	¥1,050.00	现货
50mg	¥1,645.00	现货
100mg	¥2,555.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AG-1024 (Tyrphostin)发表的1篇文献

Maeda A, .et al. , Mol Nutr Food Res. , 2014, 58(6):1177-89 PMID: 24668740

生物活性

Discription

AG-1024 (Tyrphostin) is a specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity. Exhibits lower IC50 values for IGF-1 than for the insulin receptor. Also inhibits insulin-stimulated cellular proliferation.

Targets

Target	Value

产品信息

目录号	A11400
分子式	C14H13BrN2O
分子量	305.2
CAS号	65678-07-1
SMILES	CC(C)(C)C1=C(C(=CC(=C1)C=C(C#N)C#N)Br)O
其他名称	AG1024
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	59 mg/mL (193.33 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.77 mL	163.83 mL	327.65 mL
0.5 mM	6.55 mL	32.77 mL	65.53 mL
1 mM	3.28 mL	16.38 mL	32.77 mL
5 mM	0.66 mL	3.28 mL	6.55 mL

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