AG-1024 (Tyrphostin)

目录号: A11400

IGF-1R Inhibitor

AG-1024 (Tyrphostin) Chemical Structure

CAS NO. 65678-07-1

AG-1024 (Tyrphostin) is a specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity. Exhibits lower IC50 values for IGF-1 than for the insulin receptor. Also inhibits insulin-stimulated cellular proliferation.

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,100.00
25 mg
¥ 2,200.00
50 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AG-1024 (Tyrphostin) is a specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity. Exhibits lower IC50 values for IGF-1 than for the insulin receptor. Also inhibits insulin-stimulated cellular proliferation.
Targets
IGF-1R Insulin Receptor
7 μM57 μM
In vitro (25°C) DMSO 61 mg/mL (199.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.77 mL 163.83 mL 327.65 mL
0.5 mM 6.55 mL 32.77 mL 65.53 mL
1 mM 3.28 mL 16.38 mL 32.77 mL
5 mM 0.66 mL 3.28 mL 6.55 mL

*The above data is based on the productmolecular weight 305.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11400
MECHANISM OF ACTION Inhibitor
M. Wt 305.2
Formula C14H13BrN2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 65678-07-1
Synonyms AG1024
SMILES CC(C)(C)C1=C(C(=CC(=C1)C=C(C#N)C#N)Br)O

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