AG-1478 (Tyrphostin AG-1478)

目录号: A11022

EGFR Inhibitor

AG-1478 (Tyrphostin AG-1478)

AG-1478 (Tyrphostin AG-1478) Chemical Structure

CAS NO. 153436-53-4

AG-1478 (Tyrphostin AG-1478) is an inhibitor of EGFR kinase with an IC50 value of 3 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 700.00
25 mg
¥ 1,500.00
50 mg
¥ 2,500.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AG-1478 (Tyrphostin AG-1478) is an inhibitor of EGFR kinase with an IC50 value of 3 nM.
Targets
EGFR (Cell-free assay) HER2 (Cell-free assay) PDGFR (Cell-free assay)
3 nM>100 μM>100 μM
In vitro (25°C) DMSO 25 mg/mL (79.17 mM)
Water <1 mg/mL (<1 mM)
Ethanol 13 mg/mL (41.17 mM)
In vivo 15% Captisol 15% Captisol
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.67 mL 158.33 mL 316.66 mL
0.5 mM 6.33 mL 31.67 mL 63.33 mL
1 mM 3.17 mL 15.83 mL 31.67 mL
5 mM 0.63 mL 3.17 mL 6.33 mL

*The above data is based on the productmolecular weight 315.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11022
MECHANISM OF ACTION Inhibitor
M. Wt 315.8
Formula C16H14ClN3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 153436-53-4
Synonyms AG1478, AG 1478
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC

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