AG-17

目录号: A11949

EGFR inhibitor

AG-17

AG-17 Chemical Structure

CAS NO. 10537-47-0

AG-17 is an inhibitor of EGF receptor kinase with an IC50 value of 460 µM in the human epidermoid carcinoma cell line A431.

库存: 现货

规格 价格 数量
50 mg
¥ 600.00
100 mg
¥ 1,100.00
200 mg
¥ 2,000.00
500 mg
¥ 5,000.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AG-17 is an inhibitor of EGF receptor kinase with an IC50 value of 460 µM in the human epidermoid carcinoma cell line A431.
Targets
PDGFR EGFR
0.5 μM460 μM
In vitro DMSO 56 mg/mL (198.31 mM)
Water <1 mg/mL (<1 mM)
Ethanol 56 mg/mL (198.31 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.41 mL 177.05 mL 354.11 mL
0.5 mM 7.08 mL 35.41 mL 70.82 mL
1 mM 3.54 mL 17.71 mL 35.41 mL
5 mM 0.71 mL 3.54 mL 7.08 mL

*The above data is based on the productmolecular weight 282.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11949
MECHANISM OF ACTION Inhibitor
M. Wt 282.4
Formula C18H22N2O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 10537-47-0
Synonyms NSC 242557, RG-50872, GCP 5126, SF 6847, Tyrphostin AG-17, Malonoben, Tyrphostin 9
SMILES CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C#N

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