AG-18 (Tyrphostin 23)
目录号: A15940
EGFR 抑制剂
AG-18 是一种表皮生长因子(EGF)受体激酶的抑制剂,在人类表皮癌细胞系 A431 中的 IC50 值为 35 μM。
| Discription | AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 ,M in the human epidermoid carcinoma cell line A431. | ||
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| 目录号 | A15940 |
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| 分子式 | C10H6N2O2 |
| 分子量 | 186.17 |
| CAS号 | 118409-57-7 |
| SMILES | N#C/C(C#N)=C/C1=CC=C(O)C(O)=C1 |
| 其他名称 | RG-50810, RG-50858, TX 825, Tyrphostin 23, Tyrphostin A23, Tyrphostin AG-18 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 34 mg/mL (182.63 mM) | |
| Water | Insoluble | ||
| Ethanol | 34 mg/mL (182.63 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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| 0.1 mM | 53.71 mL | 268.57 mL | 537.14 mL |
| 0.5 mM | 10.74 mL | 53.71 mL | 107.43 mL |
| 1 mM | 5.37 mL | 26.86 mL | 53.71 mL |
| 5 mM | 1.07 mL | 5.37 mL | 10.74 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2