AG-120

Name: AG-120
SKU: A15869

目录号: A15869

Dehydrogenase 抑制剂

AG-120 Chemical Structure

CAS NO. 1448347-49-6

AG-120是1型异柠檬酸脱氢酶（IDH1）的抑制剂，具有潜在的抗肿瘤活性。

库存：现货

规格	价格	数量
5 mg	￥ 850.00
10 mg	￥ 1,550.00
25 mg	￥ 3,000.00

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生物活性

AG-120是1型异柠檬酸脱氢酶（IDH1）的抑制剂，具有潜在的抗肿瘤活性。

靶点信息

IDH1

溶解度 *

In vitro	DMSO	92 mg/mL (157.81 mM)
	Water	Insoluble
	Ethanol	92 mg/mL (157.81 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.15 mL	85.77 mL	171.54 mL
0.5 mM	3.43 mL	17.15 mL	34.31 mL
1 mM	1.72 mL	8.58 mL	17.15 mL
5 mM	0.34 mL	1.72 mL	3.43 mL

*The above data is based on the productmolecular weight 582.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15869
作用机制	Inhibitor (抑制剂)
M. Wt	582.96
Formula	C28H22ClF3N6O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1448347-49-6
Synonyms	Ivosidenib
SMILES	O=C([C@H](CC1)N(C2=NC=CC(C#N)=C2)C1=O)N([C@@H](C3=CC=CC=C3Cl)C(NC4CC(F)(F)C4)=O)C5=CC(F)=CN=C5