AG-494
目录号: A17142
EGFR 抑制剂
AG-494 是一种表皮生长因子受体激酶的抑制剂，在 HT-22 细胞中的 IC50 值为 1 μM。
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生物活性
| Discription | AG-494 is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 1 μM in HT-22 cells. | ||
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产品信息
| 目录号 | A17142 |
|---|---|
| 分子式 | C16H12N2O3 |
| 分子量 | 280.28 |
| CAS号 | 133550-35-3 |
| SMILES | O=C(NC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2 |
| 其他名称 | Tyrphostin AG-494, AG494, AG 494 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 50 mg/mL (178.39 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL (14.27 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.68 mL | 178.39 mL | 356.79 mL |
| 0.5 mM | 7.14 mL | 35.68 mL | 71.36 mL |
| 1 mM | 3.57 mL | 17.84 mL | 35.68 mL |
| 5 mM | 0.71 mL | 3.57 mL | 7.14 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 133550-35-3 | 133550-35-3 供应商 | 133550-35-3 花费 | 133550-35-3 生产商 | 订购 133550-35-3 | 133550-35-3 代理商