AGI-6780

目录号: A12903

IDH2 R140Q 抑制剂

AGI-6780

AGI-6780 Chemical Structure

CAS NO. 1432660-47-3

AGI-6780是有效的选择性IDH2突变抑制剂,IC50值为23 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
25 mg
¥ 2,800.00
50 mg
¥ 5,000.00
10mM * 1mL in DMSO
¥ 1,360.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AGI-6780是有效的选择性IDH2突变抑制剂,IC50值为23 nM。
靶点信息
IDH2 R140Q mutant
23 nM
In vitro DMSO 87 mg/mL (180.68 mM)
Water Insoluble
Ethanol 87 mg/mL (180.68 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.77 mL 103.84 mL 207.68 mL
0.5 mM 4.15 mL 20.77 mL 41.54 mL
1 mM 2.08 mL 10.38 mL 20.77 mL
5 mM 0.42 mL 2.08 mL 4.15 mL

*The above data is based on the productmolecular weight 481.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12903
作用机制 Inhibitor (抑制剂)
M. Wt 481.5
Formula C21H18F3N3O3S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1432660-47-3
Synonyms AGI6780
SMILES C1CC1NS(=O)(=O)C2=CC(=C(C=C2)C3=CSC=C3)NC(=O)NC4=CC=CC(=C4)C(F)(F)F

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