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IDH2 R140Q 抑制剂

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产品目录号: A12903


产品名 目录号 价格 数量
AGI-6780 5mg A12903-5
¥ 800.00
AGI-6780 10mg A12903-10
¥ 1,400.00
AGI-6780 25mg A12903-25
¥ 2,800.00
AGI-6780 50mg A12903-50
¥ 5,000.00
AGI-6780 10mM * 1mL in DMSO A12903-10mM-D
¥ 1,360.00



AGI-6780 is a potent, selective inhibitor of mutant IDH2 with an IC50 value of 23 nM.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A12903
Mechanism of action Inhibitor
分子量 481.5
化学分子式 C21H18F3N3O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1432660-47-3
Synonyms AGI6780
SMILES code C1CC1NS(=O)(=O)C2=CC(=C(C=C2)C3=CSC=C3)NC(=O)NC4=CC=CC(=C4)C(F)(F)F
化学名称 N-?cyclopropyl-?4-?(3-?thienyl)-?3-?[[[[3-?(trifluoromethyl)phenyl]amino]carbonyl]amino]-?benzenesulfonamide


AGI-6780 is a potent, selective inhibitor of mutant IDH2 with an IC50 value of 23 nM.
IDH2 R140Q mutant
23 nM


Solubility (25°C)* In vitro DMSO 96 mg/mL (199.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol 96 mg/mL (199.37 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.77 mL 103.84 mL 207.68mL
0.5 mM 4.15 mL 20.77 mL 41.54 mL
1 mM 2.08 mL 10.38 mL 20.77 mL
5 mM 0.42 mL 2.08 mL 4.15 mL

*The above data is based on the productmolecular weight 481.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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