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AGN 196996

RAR?? 拮抗剂

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产品目录号: A16294

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AGN 196996 5mg A16294-5
¥ 3,200.00
AGN 196996 10mg A16294-10
¥ 4,800.00
AGN 196996 50mg A16294-50
¥ 14,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).

AGN 196996

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Chemical Information

目录号 A16294
Mechanism of action Antagonist
分子量 482.32
化学分子式 C24H20BrNO5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 958295-17-5
Synonyms AGN196996, AGN-196996
SMILES code CCOC1=C(C=C(C=C1Br)C(=O)NC2=CC=C(C=C2)C(=O)O)C(=O)C3=CC=C(C=C3)C
化学名称 4-[[3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid

生物活性

Description
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.73 mL 103.67 mL 207.33mL
0.5 mM 4.15 mL 20.73 mL 41.47 mL
1 mM 2.07 mL 10.37 mL 20.73 mL
5 mM 0.41 mL 2.07 mL 4.15 mL

*The above data is based on the productmolecular weight 482.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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