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AGN 205728

RAR?? 拮抗剂

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产品目录号: A16296


产品名 目录号 价格 数量
AGN 205728 5mg A16296-5
¥ 3,200.00
AGN 205728 10mg A16296-10
¥ 4,800.00
AGN 205728 50mg A16296-50
¥ 14,000.00



AGN 205728 is a potent and selective RARγ antagonist with Ki/IC95 values of 3 nM/ 0.6 nM; no inhibiton on RARα and RARβ.

AGN 205728




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Chemical Information

目录号 A16296
Mechanism of action Antagonist
分子量 437.53
化学分子式 C29H27NO3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 859498-05-8
Synonyms AGN205728, AGN-205728
SMILES code CC1=CC=C(C=C1)C2=CCC(C)(C)C3=C2C=CC(=C3)/C(=N/O)/C=C/C4=CC=C(C=C4)C(=O)O
化学名称 Benzoic acid, 4-[(1E,3E)-3-[7,8-dihydro-8,8-dimethyl-5-(4-methylphenyl)-2-naphthalenyl]-3-(hydroxyimino)-1-propen-1-yl]-


AGN 205728 is a potent and selective RARγ antagonist with Ki/IC95 values of 3 nM/ 0.6 nM; no inhibiton on RARα and RARβ.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.86 mL 114.28 mL 228.56mL
0.5 mM 4.57 mL 22.86 mL 45.71 mL
1 mM 2.29 mL 11.43 mL 22.86 mL
5 mM 0.46 mL 2.29 mL 4.57 mL

*The above data is based on the productmolecular weight 437.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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