AGN-242428

Name: AGN-242428
SKU: A16935

目录号: A16935

RORγt 抑制剂

AGN-242428 Chemical Structure

CAS NO. 1802706-04-2

AGN-242428，也称为VTP-43742，是一种有效的，选择性的和口服活性的RORγ抑制剂，Ki值为<100 nM。用于治疗自身免疫性疾病，包括多发性硬化症和牛皮癣。

库存：现货

规格	价格	数量
1 mg	￥ 8,000.00
2 mg	￥ 15,000.00
5 mg	￥ 27,000.00

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生物活性

AGN-242428，也称为VTP-43742，是一种有效的，选择性的和口服活性的RORγ抑制剂，Ki值为<100 nM。用于治疗自身免疫性疾病，包括多发性硬化症和牛皮癣。

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.09 mL	90.47 mL	180.95 mL
0.5 mM	3.62 mL	18.09 mL	36.19 mL
1 mM	1.81 mL	9.05 mL	18.09 mL
5 mM	0.36 mL	1.81 mL	3.62 mL

*The above data is based on the productmolecular weight 552.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16935
作用机制	Inhibitor (抑制剂)
M. Wt	552.65
Formula	C27H35F3N4O3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1802706-04-2
Synonyms	VTP-43742, VTP 43742, VTP43742, AGN242428, AGN 242428
SMILES	CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3[C@H](C(C)C)N(C[C@H]4CC[C@@H](CC4)C(F)(F)F)Cc3c2)nc1