Agomelatine
目录号: A10048
5-HT Receptor 拮抗剂
Agomelatine 是一种褪黑激素受体激动剂（MT1 和 MT2 受体）和 5-HT2C 受体拮抗剂。
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生物活性
| Discription | Agomelatine is a melatonergic agonist (MT1 and MT2 receptors) and 5-HT2C antagonist. | |||||
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产品信息
| 目录号 | A10048 |
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| 分子式 | C15H17NO2 |
| 分子量 | 243.3 |
| CAS号 | 138112-76-2 |
| SMILES | CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC |
| 其他名称 | Valdoxan, Melitor, Thymanax |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 48 mg/mL (197.28 mM) | |
| Water | Insoluble | ||
| Ethanol | 48 mg/mL (197.28 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 41.1 mL | 205.51 mL | 411.02 mL |
| 0.5 mM | 8.22 mL | 41.1 mL | 82.2 mL |
| 1 mM | 4.11 mL | 20.55 mL | 41.1 mL |
| 5 mM | 0.82 mL | 4.11 mL | 8.22 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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