AKT inhibitor VIII (AKTI-1/2)

Name: AKT inhibitor VIII (AKTI-1/2)
SKU: A11286
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A11286

AKT 抑制剂

2 篇发表文献

AKT inhibitor VIII 是一种细胞渗透性和可逆的喹喔啉化合物，能够强效且选择性地抑制 Akt1/Akt2 活性（在体外激酶实验中，对 Akt1、Akt2 和 Akt3 的 IC50 分别为 58 nM、210 nM 和 2.12 μM）。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
2mg	¥385.00	现货
5mg	¥595.00	现货
10mg	¥945.00	现货
25mg	¥1,890.00	现货
50mg	¥3,150.00	现货
100mg	¥4,655.00	现货
*10mM 1mL in DMSO**	¥840.00	现货
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Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AKT inhibitor VIII (AKTI-1/2)发表的2篇文献

Bjune K, .et al. , PLoS One, 2019, Jun 19;14(6):e0218537 PMID: 31216345

Hoshiba T, .et al. , Biochim Biophys Acta, 2016, Nov;1863(11):2749-2757 PMID: 27558478

生物活性

Discription

AKT inhibitor VIII is a cell-permeable and reversible quinoxaline compound that potently and selectively inhibits Akt1/Akt2 activity (IC50 = 58 nM, 210 nM, and 2.12 μM for Akt1, Akt2, and Akt3, respectively, in in vitro kinase assays).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11286
分子式	C34H29N7O
分子量	551.6
CAS号	612847-09-3
SMILES	C1CN(CCC1N2C3=CC=CC=C3NC2=O)CC4=CC=C(C=C4)C5=NC6=CC7=C(C=C6N=C5C8=CC=CC=C8)N=CN7
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	19 mg/mL (34.44 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.13 mL	90.65 mL	181.29 mL
0.5 mM	3.63 mL	18.13 mL	36.26 mL
1 mM	1.81 mL	9.06 mL	18.13 mL
5 mM	0.36 mL	1.81 mL	3.63 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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