ALLO-2
目录号: A18698
Smo mutant 拮抗剂
ALLO-2 是一种强效的抗药性Smoothened (Smo)突变拮抗剂,能够抑制在TM3-Gli-Luc细胞中由Smo激动剂Hh-Ag1.5诱导的荧光素酶表达,其IC50为6纳摩尔。
| Discription | ALLO-2 is a potent drug-resistant Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM. |
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| 目录号 | A18698 |
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| 分子式 | C18H12F3N5O |
| 分子量 | 371.32 |
| CAS号 | 1357350-60-7 |
| SMILES | FC(F)(OC1=CC=C(C=C1)C2=NC(NC3=CC4=C(C=C3)NN=C4)=NC=C2)F |
| 其他名称 | ALLO2, ALLO 2 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2