Alobresib
目录号: A19246
BET bromodomain 抑制剂
Alobresib（GS-5829）是一种 BET溴结构域抑制剂，对于表达过量c-Myc的复发性/化疗耐药性子宫浆液性癌症（USC）具有高效的治疗作用。
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生物活性
| Discription | Alobresib (GS-5829) is a BET bromodomain inhibitor, which represents a highly effective therapeutics agent against recurrent/chemotherapy resistant uterine serous carcinoma (USC) overexpressing c-Myc. |
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产品信息
| 目录号 | A19246 |
|---|---|
| 分子式 | C26H23N5O2 |
| 分子量 | 437.49 |
| CAS号 | 1637771-14-2 |
| SMILES | OC(C1=CC=CC=N1)(C2=CC=CC=N2)C3=C(NC(C4CC4)=N5)C5=CC(C(C(C)=NO6)=C6C)=C3 |
| 其他名称 | GS-5829, GS 5829, GS5829 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 76 mg/mL (173.72 mM) | |
| Water | <1 mg/mL | ||
| Ethanol | 10 mg/mL (22.85 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.86 mL | 114.29 mL | 228.58 mL |
| 0.5 mM | 4.57 mL | 22.86 mL | 45.72 mL |
| 1 mM | 2.29 mL | 11.43 mL | 22.86 mL |
| 5 mM | 0.46 mL | 2.29 mL | 4.57 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1637771-14-2 | 1637771-14-2 供应商 | 1637771-14-2 花费 | 1637771-14-2 生产商 | 订购 1637771-14-2 | 1637771-14-2 代理商