Alogliptin

目录号: A13571

DPP-4 inhibitor

Alogliptin

Alogliptin Chemical Structure

CAS NO. 850649-61-5

Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,500.00
25 mg
¥ 3,000.00
10mM * 1mL in DMSO
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
Targets
DPP-4
<10 nM
In vitro (25°C) DMSO 68 mg/mL (200.35 mM)
Water 2 mg/mL (5.89 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.46 mL 147.32 mL 294.64 mL
0.5 mM 5.89 mL 29.46 mL 58.93 mL
1 mM 2.95 mL 14.73 mL 29.46 mL
5 mM 0.59 mL 2.95 mL 5.89 mL

*The above data is based on the productmolecular weight 339.397. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A13571
MECHANISM OF ACTION Inhibitor
M. Wt 339.397
Formula C18H21N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 850649-61-5
Synonyms SYR-322, Axagliptin hydrate
SMILES CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[C@H](C3)N

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