Alogliptin
目录号: A13571
DPP-4 抑制剂
阿格列汀是一种强效、选择性的DPP-4抑制剂，其IC50值小于10纳摩尔，对DPP-8和DPP-9的选择性超过10,000倍。
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生物活性
| Discription | Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. | |||||
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| Cell Research |
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产品信息
| 目录号 | A13571 |
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| 分子式 | C18H21N5O2 |
| 分子量 | 339.397 |
| CAS号 | 850649-61-5 |
| SMILES | CN1C(=O)C=C(N(C1=O)CC2=CC=CC=C2C#N)N3CCC[C@H](C3)N |
| 其他名称 | SYR-322, Axagliptin hydrate |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 59 mg/mL (173.84 mM) | |
| Water | 16 mg/mL (47.14 mM) | ||
| Ethanol | 59 mg/mL (173.84 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.46 mL | 147.32 mL | 294.64 mL |
| 0.5 mM | 5.89 mL | 29.46 mL | 58.93 mL |
| 1 mM | 2.95 mL | 14.73 mL | 29.46 mL |
| 5 mM | 0.59 mL | 2.95 mL | 5.89 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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