alpha-Amyloid Precursor Protein Modulator

Name: alpha-Amyloid Precursor Protein Modulator
SKU: A13094
Price: 1085 CNY
Rating: 5 (1 reviews)

目录号: A13094

1 篇发表文献

alpha-淀粉样前体蛋白调节剂是一种细胞渗透性的苯并内酯衍生的PKC激活剂（对PKCα的Ki = 11.9 nM），即使在100 nM的浓度下，也能有效增强人类成纤维细胞中淀粉样前体蛋白（APP）的非淀粉样α-加工。

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alpha-Amyloid Precursor Protein Modulator

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规格	价格	库存
1mg	¥1,085.00	现货
2mg	¥1,225.00	现货
5mg	¥2,415.00	现货
10mg	¥4,515.00	现货
25mg	¥8,365.00	现货
*10mM 1mL in DMSO**	¥4,060.00	现货
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Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用alpha-Amyloid Precursor Protein Modulator发表的1篇文献

Shusen Wang, .et al. , Cell, 2024, Oct 31;187(22):6152-6164 PMID: 39326417

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生物活性

Discription

alpha-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblas.

Targets

Target	Value

产品信息

目录号	A13094
分子式	C27H30F3N3O3
分子量	501.5
CAS号	497259-23-1
SMILES	CC(C)[C@H]1C(=O)N[C@@H](CC2=C(N1C)C=CC(=C2)NC(=O)/C=C/C=C/C3=CC=C(C=C3)C(F)(F)F)CO
其他名称	PKC Activator V
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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