alpha-Bisabolol
目录号: A18691
alpha-Bisabolol 是一种存在于天然精油中的非毒性倍半萜醇,具有抗癌活性。alpha-Bisabolol 对 A549 非小细胞肺癌细胞(IC50=15 μM)表现出选择性抗癌效果,通过诱导细胞周期阻滞、线粒体凋亡和抑制 PI3K/Akt 信号通路来发挥作用。alpha-Bisabolol 也强烈诱导胶质瘤细胞的凋亡。
Discription | alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells. |
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目录号 | A18691 |
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分子式 | C15H26O |
分子量 | 222.37 |
CAS号 | 515-69-5 |
SMILES | C/C(C)=C\CC[C@@](O)([C@@H]1CCC(C)=CC1)C |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2