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α-Hemolysin (Staphylococcus aureus)

目录号: A22991
α-Hemolysin (Staphylococcus aureus) 是由 Staphylococcus aureus 分泌的最具特征性的毒力因子之一,这种多肽能够破坏宿主细胞的质膜。当 α-Hemolysin 结合到细胞表面后,其单体会组装成一个同源七聚体,形成一个前端孔,然后转变为成熟的跨膜孔水通道,允许 K+Ca2+ 离子运输,导致目标细胞的坏死性死亡。
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规格 价格 库存 数量
500µg
¥6,111.00
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Discription α-Hemolysin (Staphylococcus aureus) is one of the most characteristic virulence factors secreted by Staphylococcus aureus, a polypeptide capable of destroying the host cell plasma membrane. After α-Hemolysin binds to the cell surface, its monomers assemble into a homoheptamer to form a front pore, which then transforms into a mature transmembrane pore water channel, allowing K+ and Ca2+ ion transport, leading to necrotic death of target cells.
产品信息
目录号 A22991
分子式 C1269H1971N339O400S6
分子量 28569.06
CAS号 94716-94-6
Sequence Ala-Asp-Ser-Asp-Ile-Asn-Ile-Lys-Thr-Gly-Thr-Thr-Asp-Ile-Gly-Ser-Asn-Thr-Thr-Val-Lys-Thr-Gly-Asp-Leu-Val-Thr-Tyr-Asp-Lys-Glu-Asn-Gly-Met-His-Lys-Lys-Val-Phe-Tyr-Ser-Phe-Ile-Asp-Asp-Lys-Asn-Ala-Ile-Lys-Lys-Leu-Leu-Val-Ile-Arg-Thr-Lys-Gly-Thr-Ile-Ala-Gly-Gln-Tyr-Arg-Val-Tyr-Ser-Glu-Glu-Gly-Ala-Asn-Lys-Ser-Gly-Leu-Ala-Trp-Pro-Ser-Ala-Phe-Lys-Val-Gln-Leu-Gln-Leu-Pro-Asp-Asn-Glu-Val-Ala-Glu-Ile-Ser-Asp-Tyr-Tyr-Pro-Arg-Asn-Ser-Ile-Asp-Thr-Lys-Glu-Tyr-Met-Ser-Thr-Leu-Thr-Tyr-Gly-Phe-Asn-Gly-Asn-Val-Thr-Gly-Asp-Asp-Thr-Gly-Lys-Ile-Gly-Gly-Leu-Ile-Gly-Ala-Asn-Val-Ser-Ile-Gly-His-Thr-Leu-Lys-Tyr-Val-Gln-Pro-Asp-Phe-Lys-Thr-Ile-Leu-Glu-Ser-Pro-Thr-Asp-Lys-Lys-Val-Gly-Trp-Lys-Val-Ile-Phe-Asn-Asn-Met-Val-Asn-Gln-Asn-Trp-Gly-Pro-Tyr-Asp-Arg-Asp-Ser-Trp-Asn-Pro-Val-Tyr-Gly-Asn-Gln-Leu-Phe-Met-Lys-Thr-Arg-Asn-Gly-Ser-Met-Lys-Ala-Ala-Asp-Asn-Phe-Leu-Asp-Pro-Asn-Lys-Ala-Ser-Ser-Leu-Leu-Ser-Ser-Gly-Phe-Ser-Pro-Asp-Phe-Ala-Thr-Val-Ile-Thr-Met-Asp-Arg-Lys-Ala-Ser-Lys-Gln-Gln-Thr-Asn-Ile-Asp-Val-Ile-Tyr-Glu-Arg-Val-Arg-Asp-Asp-Tyr-Gln-Leu-His-Trp-Thr-Ser-Thr-Asn-Trp-Lys-Gly-Thr-Asn-Thr-Lys-Asp-Lys-Trp-Thr-Asp-Arg-Ser-Ser-Glu-Arg-Tyr-Lys-Ile-Asp-Trp-Glu-Lys-Glu-Glu-Met-Thr-Asn
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