Alvelestat

目录号: A12779

neutrophil elastase inhibitor

Alvelestat Chemical Structure

CAS NO. 848141-11-7

Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (NE).

库存: 现货

规格 价格 数量
5 mg
¥ 650.00
10 mg
¥ 900.00
25 mg
¥ 1,800.00
10mM * 1mL in DMSO
¥ 1,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (NE).
Targets
neutrophil elastase neutrophil elastase
9.4 nM(Ki)12 nM
In vitro DMSO 100 mg/mL (183.3 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.33 mL 91.66 mL 183.32 mL
0.5 mM 3.67 mL 18.33 mL 36.66 mL
1 mM 1.83 mL 9.17 mL 18.33 mL
5 mM 0.37 mL 1.83 mL 3.67 mL

*The above data is based on the productmolecular weight 545.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12779
MECHANISM OF ACTION Inhibitor
M. Wt 545.5
Formula C25H22F3N5O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 848141-11-7
Synonyms AZD9668,AZD 9668,AZD-9668
SMILES CC1=C(C=C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)C(=O)NCC3=NC=C(C=C3)S(=O)(=O)C)C4=CC=NN4C

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