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Alvimopan dihydrate

??-opioid receptor 激动剂

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产品目录号: A14991

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Alvimopan dihydrate 5mg A14991-5
¥ 1,150.00
Alvimopan dihydrate 10mg A14991-10
¥ 1,950.00
Alvimopan dihydrate 50mg A14991-50
¥ 5,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Alvimopan dihydrate(LY 246736, ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.

Alvimopan dihydrate

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Chemical Information

目录号 A14991
Mechanism of action Agonist
分子量 460.56
化学分子式 C25H36N2O6
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 170098-38-1
Synonyms LY 246736 dihydrate, ADL 8-2698 dihydrate
SMILES code CC1CN(CCC1(C)C2=CC(=CC=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(=O)O.O.O
化学名称 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid,dihydrate

生物活性

Description
Alvimopan dihydrate(LY 246736, ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.71 mL 108.56 mL 217.13mL
0.5 mM 4.34 mL 21.71 mL 43.43 mL
1 mM 2.17 mL 10.86 mL 21.71 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 460.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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