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Chemical Information
| 目录号 | A14180 |
|---|---|
| Mechanism of action | Antagonist |
| 分子量 | 456.49 |
| 化学分子式 | C27H24N2O5 |
| Solubility | DMSO |
| 纯度 | >98% |
| 储存方式 | at -20°C 2 years |
| CAS No. | 1228690-36-5 |
| Synonyms | AM 095,AM-095 |
| SMILES code | CC1=NOC(=C1NC(=O)O[C@H](C)C2=CC=CC=C2)C3=CC=C(C=C3)C4=CC=C(C=C4)CC(=O)O |
| 化学名称 | 2-[4-[4-[3-methyl-4-[[(1R)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic acid |
Description |
AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 μM for mouse or recombinant human LPA1, respectively | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.91 mL | 109.53 mL | 219.06mL |
| 0.5 mM | 4.38 mL | 21.91 mL | 43.81 mL |
| 1 mM | 2.19 mL | 10.95 mL | 21.91 mL |
| 5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
*The above data is based on the productmolecular weight 456.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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