AM1241
目录号: A16397
CB2 receptor 激动剂
AM1241 是一种选择性的 大麻素 CB2 受体激动剂,其 Ki 值为 3.4 nM,对 CB1 受体的选择性高达 82 倍。
| Discription | AM1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. |
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| 目录号 | A16397 |
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| 分子式 | C22H22IN3O3 |
| 分子量 | 503.33 |
| CAS号 | 444912-48-5 |
| SMILES | CN1CCCCC1CN2C=C(C3=CC=CC=C32)C(=O)C4=C(C=CC(=C4)[N+](=O)[O-])I |
| 其他名称 | AM 1241, AM-1241 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 86 mg/mL (170.86 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.87 mL | 99.34 mL | 198.68 mL |
| 0.5 mM | 3.97 mL | 19.87 mL | 39.74 mL |
| 1 mM | 1.99 mL | 9.93 mL | 19.87 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.97 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2