Ambroxol HCl

Name: Ambroxol HCl
SKU: A16398
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A16398

Sodium Channel 抑制剂

1 篇发表文献

AmbroxolHCl 是一种强效的神经元 Na+ 通道 抑制剂，能够抑制 TTX-抗性 Na+ 电流，对于 音调阻断 和 短暂阻断 的 IC50 分别为 35.2 μM 和 22.5 μM，抑制 TTX-敏感 Na+ 电流的 IC50 为 100 μM。目前处于 第三阶段 临床试验。

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规格	价格	库存
50mg	¥175.00	现货
100mg	¥175.00	现货
500mg	¥315.00	现货
1g	¥455.00	现货
*10mM 1mL in DMSO**	¥210.00	现货
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Data Sheet

SDS

Other Forms of Ambroxol HCl

Ambroxol

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Ambroxol HCl发表的1篇文献

Giovanni Bocci, .et al. , ACS Pharmacol Transl Sci, 2020, Oct 14

生物活性

Discription	AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 uM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.

产品信息

目录号	A16398
分子式	C13H18Br2N2O.HCl
分子量	414.56
CAS号	23828-92-4
SMILES	C1CC(CCC1NCC2=CC(=CC(=C2N)Br)Br)O.Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 4 mg/mL (9.64 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.12 mL	120.61 mL	241.22 mL
0.5 mM	4.82 mL	24.12 mL	48.24 mL
1 mM	2.41 mL	12.06 mL	24.12 mL
5 mM	0.48 mL	2.41 mL	4.82 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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