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AMD-070 HCl

CXCR4 拮抗剂

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产品目录号: A14997

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AMD-070 hydrochloride 5mg A14997-5
¥ 1,400.00
AMD-070 hydrochloride 10mg A14997-10
¥ 2,500.00
AMD-070 hydrochloride 50mg A14997-50
¥ 7,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay, inhibit the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs.

AMD-070 HCl

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Chemical Information

目录号 A14997
Mechanism of action Antagonist
分子量 458.86
化学分子式 C21H30Cl3N5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 880549-30-4
Synonyms AMD070 hydrochloride, AMD 070 hydrochloride
SMILES code C1CC(C2=C(C1)C=CC=N2)N(CCCCN)CC3=NC4=CC=CC=C4N3.Cl
化学名称 N'-(1H-benzimidazol-2-ylmethyl)-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine,hydrochloride

生物活性

Description
AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay, inhibit the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.79 mL 108.97 mL 217.93mL
0.5 mM 4.36 mL 21.79 mL 43.59 mL
1 mM 2.18 mL 10.9 mL 21.79 mL
5 mM 0.44 mL 2.18 mL 4.36 mL

*The above data is based on the productmolecular weight 458.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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