AMG 208

目录号: A10063

c-Met 抑制剂

AMG 208

AMG 208 Chemical Structure

CAS NO. 1002304-34-8

AMG 208是一种新型c-Met抑制剂,可抑制c-Met的配体依赖性和配体依赖性活化,从而抑制其酪氨酸激酶活性。

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,860.00
100 mg
¥ 7,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AMG 208是一种新型c-Met抑制剂,可抑制c-Met的配体依赖性和配体依赖性活化,从而抑制其酪氨酸激酶活性。
靶点信息
c-Met
9 nM
In vitro (25°C) DMSO 0.22 mg/mL (0.57 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.08 mL 130.41 mL 260.82 mL
0.5 mM 5.22 mL 26.08 mL 52.16 mL
1 mM 2.61 mL 13.04 mL 26.08 mL
5 mM 0.52 mL 2.61 mL 5.22 mL

*The above data is based on the productmolecular weight 383.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10063
作用机制 Inhibitor (抑制剂)
M. Wt 383.4
Formula C22H17N5O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1002304-34-8
Synonyms AMG208, AMG-208
SMILES COC1=CC2=NC=CC(=C2C=C1)OCC3=NN=C4N3N=C(C=C4)C5=CC=CC=C5

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