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AMG 337

MET 抑制剂

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产品目录号: A16400


产品名 目录号 价格 数量
AMG 337 5mg A16400-5
¥ 900.00
AMG 337 10mg A16400-10
¥ 1,600.00
AMG 337 50mg A16400-50
¥ 4,800.00



AMG 337 is an oral, small molecule, ATP-competitive, highly selective inhibitor of the MET receptor.

AMG 337




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Chemical Information

目录号 A16400
Mechanism of action Inhibitor
分子量 463.46
化学分子式 C23H22FN7O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1173699-31-4
Synonyms AMG337, AMG-337
SMILES code CN1N=CC(C2=CN3C([C@@H](C)N4C=CC(N=CC(OCCOC)=C5)=C5C4=O)=NN=C3C(F)=C2)=C1
化学名称 (R)-6-(1-(8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one


AMG 337 is an oral, small molecule, ATP-competitive, highly selective inhibitor of the MET receptor.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.58 mL 107.88 mL 215.77mL
0.5 mM 4.32 mL 21.58 mL 43.15 mL
1 mM 2.16 mL 10.79 mL 21.58 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 463.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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