AMG-47a

目录号: A13167

Lck inhibitor

AMG-47a Chemical Structure

CAS NO. 882663-88-9

AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,600.00
25 mg
¥ 6,000.00
50 mg
¥ 10,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.67 mL 93.36 mL 186.72 mL
0.5 mM 3.73 mL 18.67 mL 37.34 mL
1 mM 1.87 mL 9.34 mL 18.67 mL
5 mM 0.37 mL 1.87 mL 3.73 mL

*The above data is based on the productmolecular weight 535.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13167
MECHANISM OF ACTION Inhibitor
M. Wt 535.56
Formula C29H28F3N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 882663-88-9
Synonyms AMG47a, Geneticin
SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=CN=C(N=C4C=C3)NCCN5CCOCC5

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