AMG-510 (Sotorasib)

Name: AMG-510 (Sotorasib)
SKU: A19021
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A19021

KRAS G12C covalent 抑制剂

AMG-510 是一种强效的、口服生物利用度高的、选择性 KRAS G12C 共价抑制剂，具有抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥245.00	现货
5mg	¥455.00	现货
10mg	¥840.00	现货
25mg	¥1,610.00	现货
50mg	¥2,695.00	现货
100mg	¥3,325.00	现货
500mg	¥7,525.00	现货
1g	¥9,975.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

生物活性

Discription

AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19021
分子式	C30H30F2N6O3
分子量	560.59
CAS号	2296729-00-3
SMILES	O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C(C5=C(O)C=CC=C5F)=N4)=O)CC1
其他名称	AMG 510, AMG510, Sotorasib
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	90 mg/mL (160.54 mM)
	Water	Insoluble
	Ethanol	90 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.84 mL	89.19 mL	178.38 mL
0.5 mM	3.57 mL	17.84 mL	35.68 mL
1 mM	1.78 mL	8.92 mL	17.84 mL
5 mM	0.36 mL	1.78 mL	3.57 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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