AMG-925

CDK4, FLT3

目录号: A14025

Dual FLT3/CDK4 inhibitor

AMG-925

AMG-925 Chemical Structure

CAS NO. 1401033-86-0

AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor.

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,500.00
25 mg
¥ 2,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor.
Targets
FLT3 CDK4 CDK1
1 nM3 nM2.22 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.21 mL 106.03 mL 212.07 mL
0.5 mM 4.24 mL 21.21 mL 42.41 mL
1 mM 2.12 mL 10.6 mL 21.21 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A14025
MECHANISM OF ACTION Inhibitor
M. Wt 471.55
Formula C26H29N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1401033-86-0
Synonyms AMG925, AMG 925
SMILES CC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5

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