AMG-925
目录号: A14025
Dual FLT3/CDK4 抑制剂
AMG-925 是一种高效、选择性和生物可利用的 FLT3/细胞周期依赖性激酶4 (CDK4) 双激酶抑制剂。
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生物活性
| Discription | AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor. | |||||
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产品信息
| 目录号 | A14025 |
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| 分子式 | C26H29N7O2 |
| 分子量 | 471.55 |
| CAS号 | 1401033-86-0 |
| SMILES | CC1CCC(CC1)N2C3=C(C=CN=C3)C4=CN=C(N=C42)NC5=NC6=C(CN(CC6)C(=O)CO)C=C5 |
| 其他名称 | AMG925, AMG 925 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 0.01 mg/mL (0.02 mM) | |
| Water | <1 mg/mL | ||
| Ethanol | Insoluble | ||
| In vivo | 2% hydroxypropyl methylcellulose+1% Tween 80 | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.21 mL | 106.03 mL | 212.07 mL |
| 0.5 mM | 4.24 mL | 21.21 mL | 42.41 mL |
| 1 mM | 2.12 mL | 10.6 mL | 21.21 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1401033-86-0 | 1401033-86-0 供应商 | 1401033-86-0 花费 | 1401033-86-0 生产商 | 订购 1401033-86-0 | 1401033-86-0 代理商