AMG232

目录号: A14394

MDM2 抑制剂

AMG232 Chemical Structure

CAS NO. 1352066-68-2

AMG 232 is a highly potent, selective and orally bioavailable piperidinone inhibitor of the MDM2-p53 interaction((SPR KD= 0.045 nM, SJSA-1 EdU IC50=9.1 nM).

库存: 缺货

规格 价格
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
25 mg
¥ 4,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AMG 232 is a highly potent, selective and orally bioavailable piperidinone inhibitor of the MDM2-p53 interaction((SPR KD= 0.045 nM, SJSA-1 EdU IC50=9.1 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.59 mL 87.94 mL 175.89 mL
0.5 mM 3.52 mL 17.59 mL 35.18 mL
1 mM 1.76 mL 8.79 mL 17.59 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 568.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14394
MECHANISM OF ACTION Inhibitor
M. Wt 568.55
Formula C28H35Cl2NO5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1352066-68-2
Synonyms AMG-232, AMG 232
SMILES CC(C)[C@@H](CS(=O)(=O)C(C)C)N1[C@@H]([C@H](C[C@](C1=O)(C)CC(=O)O)C2=CC(=CC=C2)Cl)C3=CC=C(C=C3)Cl

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