AMG319

目录号: A15901

PI3Kδ inhibitor

AMG319 Chemical Structure

CAS NO. 1608125-21-8

AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
25 mg
¥ 3,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
靶点信息
PI3Kδ PI3Kγ PI3Kβ PI3Kα
18 nM850 nM2.7μM33 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.95 mL 129.74 mL 259.47 mL
0.5 mM 5.19 mL 25.95 mL 51.89 mL
1 mM 2.59 mL 12.97 mL 25.95 mL
5 mM 0.52 mL 2.59 mL 5.19 mL

*The above data is based on the productmolecular weight 385.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15901
MECHANISM OF ACTION Inhibitor
M. Wt 385.4
Formula C21H16FN7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1608125-21-8
Synonyms AMG-319, AMG 319
SMILES C[C@@](NC1=NC=NC2=C1N=CN2)([H])C(C=C3C=CC(F)=CC3=N4)=C4C5=CC=CC=N5

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