AMG319
目录号: A15901
PI3Kδ 抑制剂
AMG319 是一种强效且选择性的 PI3Kδ 抑制剂，IC50 为 18 nM，对其他 PI3Ks 的选择性超过 47 倍。目前处于 Phase 2 阶段。
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生物活性
| Discription | AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2. | |||||
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| Cell Research |
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产品信息
| 目录号 | A15901 |
|---|---|
| 分子式 | C21H16FN7 |
| 分子量 | 385.4 |
| CAS号 | 1608125-21-8 |
| SMILES | C[C@@](NC1=NC=NC2=C1N=CN2)([H])C(C=C3C=CC(F)=CC3=N4)=C4C5=CC=CC=N5 |
| 其他名称 | AMG-319, AMG 319 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 72 mg/mL (186.82 mM) | |
| Water | Insoluble | ||
| Ethanol | 72 mg/mL (186.82 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.95 mL | 129.74 mL | 259.47 mL |
| 0.5 mM | 5.19 mL | 25.95 mL | 51.89 mL |
| 1 mM | 2.59 mL | 12.97 mL | 25.95 mL |
| 5 mM | 0.52 mL | 2.59 mL | 5.19 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1608125-21-8 | 1608125-21-8 供应商 | 1608125-21-8 花费 | 1608125-21-8 生产商 | 订购 1608125-21-8 | 1608125-21-8 代理商