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PI3K?? 抑制剂

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产品目录号: A15901


产品名 目录号 价格 数量
AMG319 5mg A15901-5
¥ 900.00
AMG319 10mg A15901-10
¥ 1,600.00
AMG319 25mg A15901-25
¥ 3,500.00



AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.





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Chemical Information

目录号 A15901
Mechanism of action Inhibitor
分子量 385.4
化学分子式 C21H16FN7
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1608125-21-8
Synonyms AMG-319, AMG 319
SMILES code C[C@@](NC1=NC=NC2=C1N=CN2)([H])C(C=C3C=CC(F)=CC3=N4)=C4C5=CC=CC=N5
化学名称 N-((S)-1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine


AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.
18 nM850 nM2.7μM33 μM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.95 mL 129.74 mL 259.47mL
0.5 mM 5.19 mL 25.95 mL 51.89 mL
1 mM 2.59 mL 12.97 mL 25.95 mL
5 mM 0.52 mL 2.59 mL 5.19 mL

*The above data is based on the productmolecular weight 385.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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