AMG517

Name: AMG517
SKU: A12727

目录号: A12727

TRPV1 拮抗剂

Product Citations (2)

AMG517 Chemical Structure

CAS NO. 659730-32-2

AMG 517是有效的选择性TRPV1拮抗剂。

库存：现货

规格	价格	数量
5 mg	￥ 900.00
10 mg	￥ 1,600.00
25 mg	￥ 3,000.00
50 mg	￥ 5,000.00
10mM * 1mL in DMSO	￥ 1,360.00

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生物活性

AMG 517是有效的选择性TRPV1拮抗剂。

靶点信息

TRPV1
1 nM-2 nM

溶解度 *

In vitro (25°C)	DMSO	84 mg/mL (195.16 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	10% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.23 mL	116.17 mL	232.34 mL
0.5 mM	4.65 mL	23.23 mL	46.47 mL
1 mM	2.32 mL	11.62 mL	23.23 mL
5 mM	0.46 mL	2.32 mL	4.65 mL

*The above data is based on the productmolecular weight 430.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12727
作用机制	Antagonist (拮抗剂)
M. Wt	430.4
Formula	C20H13F3N4O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	659730-32-2
Synonyms	AMG 517, AMG-517
SMILES	CC(=O)NC1=NC2=C(C=CC=C2S1)OC3=NC=NC(=C3)C4=CC=C(C=C4)C(F)(F)F