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Hmt1p/PRMT1 抑制剂

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产品目录号: A15916


产品名 目录号 价格 数量
AMI-1 5mg A15916-5
¥ 750.00
AMI-1 10mg A15916-10
¥ 1,400.00
AMI-1 25mg A15916-25
¥ 2,800.00



AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 uM and 8.8 uM for yeast Hmt1p and human PRMT1, respectively.





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Chemical Information

目录号 A15916
Mechanism of action Inhibitor
分子量 548.45
化学分子式 C21H14N2Na2O9S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 20324-87-2
Synonyms AMI 1, AMI1, AMI-1 disodium salt
SMILES code O=C(NC1=CC2=CC(S(=O)([O-])=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)([O-])=O)=CC(O)=C4C=C3.[Na+].[Na+]
化学名称 7,7'-(carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid],sodium salt (1)


AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 uM and 8.8 uM for yeast Hmt1p and human PRMT1, respectively.
yeast Hmt1p human PRMT1
3.0 μM8.8 μM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.23 mL 91.17 mL 182.33mL
0.5 mM 3.65 mL 18.23 mL 36.47 mL
1 mM 1.82 mL 9.12 mL 18.23 mL
5 mM 0.36 mL 1.82 mL 3.65 mL

*The above data is based on the productmolecular weight 548.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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