Amitriptyline HCl

Name: Amitriptyline HCl
SKU: A16404
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A16404

Amitriptyline 抑制 5-羟色胺受体（serotonin receptor）、去甲肾上腺素受体（norepinephrine receptor）、5-HT4、5-HT2 和 sigma 1 受体，其半抑制浓度（IC50）分别为 3.45 nM、13.3 nM、7.31 nM、235 nM 和 287 nM。

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Data Sheet

SDS

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生物活性

Discription

Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.

Targets

Target	Value

产品信息

目录号	A16404
分子式	C20H23N.HCl
分子量	313.86
CAS号	549-18-8
SMILES	CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	56 mg/mL (178.42 mM)
	Water	13 mg/mL (41.42 mM)
	Ethanol	56 mg/mL (178.42 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.86 mL	159.31 mL	318.61 mL
0.5 mM	6.37 mL	31.86 mL	63.72 mL
1 mM	3.19 mL	15.93 mL	31.86 mL
5 mM	0.64 mL	3.19 mL	6.37 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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