Amlodipine besylate (Norvasc)

Name: Amlodipine besylate (Norvasc)
SKU: A10069
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A10069

L-type calcium channel blocker

Amlodipine-besylate 是一种 L型钙通道阻断剂，具有降血压的特性。它能抑制去极化大鼠主动脉中由Ca2+引起的收缩（IC50 = 1.9 nM），并在心血管疾病中显示出保护血管的效果。

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Grouped product items
规格	价格	库存
500mg	¥175.00	现货
1g	¥315.00	现货
5g	¥630.00	现货
*10mM 1mL in DMSO**	¥210.00	现货
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Data Sheet

SDS

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生物活性

Discription

Amlodipine-besylate is L-type calcium channel blocker that displays antihypertensive properties. It inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10069
分子式	C20H25ClN2O5.C6H6O3S
分子量	567.1
CAS号	111470-99-6
SMILES	CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O
其他名称	Istin, Norvasc
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	102 mg/mL (179.87 mM)
	Water	Insoluble
	Ethanol	13 mg/mL (22.92 mM)
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.63 mL	88.17 mL	176.34 mL
0.5 mM	3.53 mL	17.63 mL	35.27 mL
1 mM	1.76 mL	8.82 mL	17.63 mL
5 mM	0.35 mL	1.76 mL	3.53 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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