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Amorolfine HCl

Antifungal compound

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产品目录号: A10072

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Amorolfine Hydrochloride 10mg A10072-10
¥ 1,000.00
Amorolfine Hydrochloride 25mg A10072-25
¥ 2,000.00
Amorolfine Hydrochloride 50mg A10072-50
¥ 3,200.00
Amorolfine Hydrochloride 100mg A10072-100
¥ 5,500.00
Amorolfine HCl 10mM * 1mL in DMSO A10072-10mM-D
¥ 940.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Amorolfine hydrochloride, is a morpholine antifungal reagent that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes.

Amorolfine HCl

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Chemical Information

目录号 A10072
Mechanism of action
分子量 354.0
化学分子式 C21H36ClNO
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 78613-38-4
Synonyms Amorolfin, Curanail, Loceryl, Locetar, Odenil
SMILES code CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2C[C@H](O[C@H](C2)C)C.Cl
化学名称 (+/-)-cis-2,6-Dimethyl-4-[2-methyl-3-(p-tert-pentylphenyl)propyl]morpholine hydrochloride

生物活性

Description
Amorolfine hydrochloride, is a morpholine antifungal reagent that inhibits D14 reductase and D7-D8 isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes.

溶解性

Solubility (25°C)* In vitro DMSO 28 mg/mL (79.1 mM)
Water 9 mg/mL (25.42 mM)
Ethanol 71 mg/mL (200.58 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.25 mL 141.24 mL 282.49mL
0.5 mM 5.65 mL 28.25 mL 56.5 mL
1 mM 2.82 mL 14.12 mL 28.25 mL
5 mM 0.56 mL 2.82 mL 5.65 mL

*The above data is based on the productmolecular weight 354.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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