Amphotericin B

Name: Amphotericin B
SKU: A10073
Price: 175 CNY
Rating: 5 (2 reviews)

目录号: A10073

2 篇发表文献

Amphotericin B 是一种来自 Streptomyces sp. 的多烯类抗真菌抗生素。Amphotericin B 诱导 K+ 泄漏，这与其致死作用是分开的，如在人类红细胞中所示，这是由于其对 Na+/K+ 泵的抑制作用所致。

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Grouped product items
规格	价格	库存
50mg	¥175.00	现货
100mg	¥245.00	现货
500mg	¥490.00	现货
1g	¥630.00	现货
*10mM 1mL in DMSO**	¥175.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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Adooq用户使用Amphotericin B发表的2篇文献

Ilker Kiliccioglu, .et al. , Appl Biochem Biotechnol, 2025, Aug 23 PMID: 40848211

J Chen, .et al. , Biomater Sci, 2020, Jun 21;8(12):3430-3442 PMID: 32406432

生物活性

Discription

Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. Amphotericin B induces K+ leakage, which is separate from its lethal action, as was demonstrated in human erythrocytes and is due to the inhibitory effect on the Na+/K+ pump.

Targets

Target	Value

产品信息

目录号	A10073
分子式	C47H73NO17
分子量	924.1
CAS号	1397-89-3
SMILES	C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O
其他名称	Fungilin, Fungizone, AmBisome, Fungisome, Amphocil, Amphotec
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	20 mg/mL (21.64 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.82 mL	54.11 mL	108.21 mL
0.5 mM	2.16 mL	10.82 mL	21.64 mL
1 mM	1.08 mL	5.41 mL	10.82 mL
5 mM	0.22 mL	1.08 mL	2.16 mL

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