Crisaborole (AN2728)

Name: Crisaborole (AN2728)
SKU: A12776
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A12776

PDE4 抑制剂?€?

AN2728 是一种含硼的局部使用抗炎化合物，通过抑制 PDE4 活性，从而抑制 TNFalpha、IL-12、IL-23 及其他细胞因子的释放。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥210.00	现货
50mg	¥315.00	现货
100mg	¥525.00	现货
200mg	¥735.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

AN2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12776
分子式	C14H10BNO3
分子量	251.08
CAS号	906673-24-3
SMILES	B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O
其他名称	AN 2728, AN-2728
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	47 mg/mL (187.21 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	39.83 mL	199.14 mL	398.28 mL
0.5 mM	7.97 mL	39.83 mL	79.66 mL
1 mM	3.98 mL	19.91 mL	39.83 mL
5 mM	0.8 mL	3.98 mL	7.97 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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